Research Themes

Core areas where I focus my research efforts

Molecular Dynamics Simulations

Developing automated pipelines and tools for molecular dynamics simulations, PCA analysis, and Free Energy Landscape calculations to understand protein behavior and biomolecular mechanisms.

GROMACS PCA/FEL MD Analysis

Genomics & Sequence Analysis

Building tools for DNA/RNA sequence analysis, genome annotation, and variant calling to facilitate genomic research and personalized medicine.

NGS Analysis ORF Finding GC Content

Protein Structure Prediction

Leveraging deep learning models like AlphaFold and Boltz for accurate protein structure prediction and understanding protein-ligand interactions.

AlphaFold Boltz Deep Learning

Drug Discovery & Design

Applying computational methods for virtual screening, molecular docking, and ADMET prediction to accelerate the drug discovery pipeline. Utilizing GPU-accelerated tools like Uni-Dock for high-throughput screening.

Virtual Screening Uni-Dock ADMET

Bioinformatics Tool Development

Creating open-source, user-friendly tools that democratize access to computational biology methods for researchers worldwide.

Python BioPython Open Source

Machine Learning in Biology

Applying machine learning and AI techniques to biological data for pattern recognition, prediction, and classification tasks.

ML/AI Neural Networks Classification

Ongoing Projects

Current research initiatives and development work

Active

GRAVITy Project

An automated pipeline for GROMACS that streamlines molecular dynamics simulations. Features include system setup automation, protein structure rectification, parameterization, production runs, and post-simulation trajectory analysis with an integrated GUI and 3D molecular visualization.

Python, Flask, Shell 2024 - Present
Complete

Boltz2-Notebook

A streamlined Colab-based pipeline for protein structure prediction and binding affinity analysis using the Boltz2 deep learning model. Features an interactive UI and automated analysis capabilities for researchers.

Python, Jupyter 2024
Complete

Genome Inspector

A comprehensive DNA sequence analysis tool available as both desktop application (BioPython-based GUI) and web application. Performs transcription, translation, reverse complement, GC content analysis, melting temperature calculation, and more.

Python, JavaScript 2024
Planning

Future Projects

Continuously exploring new ideas at the intersection of biology and computation. Areas of interest include multi-omics integration, single-cell analysis pipelines, and AI-driven drug discovery tools.

Ideas in Development

Research Approach

How I approach computational biology problems

1

Problem Identification

Identify gaps in current bioinformatics tools and methodologies that hinder research progress, focusing on real-world usability challenges.

2

Literature Review & Analysis

Comprehensive review of existing solutions, understanding their limitations, and identifying opportunities for improvement or innovation.

3

Design & Development

Design user-centric solutions with clean interfaces, robust algorithms, and comprehensive documentation. Emphasize reproducibility and accessibility.

4

Validation & Testing

Rigorous testing with benchmark datasets, comparison with existing tools, and validation against experimental data when possible.

5

Open Source Release

Release tools as open-source with comprehensive documentation, enabling global researchers to use, modify, and contribute to the project.

Open to Collaboration

I'm always interested in collaborating on research projects, tool development, or innovative ideas at the intersection of biology and computer science. Let's work together to advance scientific discovery.

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